文章摘要

宫颈液基细胞学涂片筛查子宫内膜癌的诊断线索

作者: 1许淑霞, 1林建松, 1马宏, 1罗莹, 1吴荔香, 1祝建芳, 2许春伟
1 福建省妇幼保健院病理科,福州 350001
2 福建医科大学附属肿瘤医院病理科,福州 350014
通讯: 许淑霞 Email: 710221408@qq.com
DOI: 10.3978/j.issn.2095-6959.10.3978/j.issn.2095-6959.2017.09.024

摘要

目的:探讨宫颈液基细胞学对子宫内膜癌的诊断线索。方法:回顾性收集287例2013年7月至2015年9月组织病理诊断为子宫内膜腺癌患者的术前宫颈液基细胞涂片,对这些涂片中存在的诊断子宫内膜癌的线索进行分析。结果:287例中阴性86例,非典型腺细胞无具体指定(atypical glandular cells-not otherwise specified,AGC-NOS)55例,非典型腺细胞倾向瘤变(atypical glandular cells-favor neoplastic,AGC-FN)109例,宫内膜腺癌29例,阳性诊断占70%。结论:宫颈液基细胞学正确诊断子宫内膜癌时细胞的形态改变与组织碎片的异常形态并重,宫颈细胞学是筛查子宫内膜腺癌重要方法。
关键词: 宫颈 液基细胞学 子宫内膜癌 细胞形态 组织碎片

Diagnosis clues for liquid-based cytology test of cervical to endometrial cancer

Authors: 1Xu Shuxia, 1Lin Jiansong, 1Ma Hong, 1Luo Ying, 1Wu Lixiang, 1Zhu Jianfang, 2Xu Chunwei
1 Department of Pathology, Fujian Provincial Maternity and Children’s Hospital, Fuzhou 350001
2 Department of Pathology, Fujian Cancer Hospital, Fujian Medical University, Fuzhou 350014, China

CorrespondingAuthor: Xu Shuxia Email: 710221408@qq.com

DOI: 10.3978/j.issn.2095-6959.10.3978/j.issn.2095-6959.2017.09.024

Abstract

Objective: To investigate the diagnosis clues for liquid-based cytology test of cervical to endometrial cancer. Methods: The retrospective analysis on the diagnosis clues were performed in 287 patients from July 2013 to September 2015 with endometrial adenocarcinoma who had the liquid-based cytology test of cervical. Results: Among 287 cases, pathological diagnoses as negative were 86 cases; diagnosed as atypical glandular cells-not otherwise specified (AGC-NOS) were 55 cases; 109 cases were atypical glandular cells-favor neoplastic (AGC-N); 37 cases were endometrial adenocarcinoma, diagnosed as positive was 70%. Conclusion: The key features of endometrial cancer in cervical liquid-based preparations were the abnormal of endometrial cells and tissue fragments, cervical cytology is an important way to screening for endometrial adenocarcinoma.
Keywords: cervical liquid-based cytology endometrial carcinoma cell morphology tissue fragment