文章摘要

氨甲蝶呤宫颈预处理+宫腔镜电切术治疗子宫瘢痕妊娠的临床效果

作者: 1郭孝琼, 1周荣生, 1陆蕴龙
1 合肥市第三人民医院(安徽医科大学第三临床教学医院)妇产科,合肥 230022
通讯: 郭孝琼 Email: 88969964@qq.com
DOI: 10.3978/j.issn.2095-6959.2020.08.015

摘要

目的:探究子宫瘢痕妊娠治疗中氨甲蝶呤(methotrexate,MTX)宫颈预处理+宫腔镜电切术的应用及其临床效果。方法:纳入2017年1月至2019年12月合肥市第三人民医院的80例I型子宫瘢痕妊娠患者,按照随机数字表法分成2组。对照组(n=50)采取介入+吸宫术治疗,研究组(n=30)采取MTX宫颈预处理+宫腔镜电切手术治疗。记录并对比2组的手术时间、术中出血量、血清β-人绒毛膜促性腺激素(β-human chorionic gonadotropin,β-HCG)恢复正常时间及月经恢复时间,比较2组的临床治疗效果及并发症发生率。结果:治疗后研究组的术中出血量明显减少,手术时间、血清β-HCG恢复正常时间及月经恢复时间显著缩短,与对照组相比差异有统计学意义(P<0.05)。研究组治疗后的总有效率与对照组相比,差异有统计学意义(P<0.05)。研究组治疗后的并发症发生率与对照组相比,差异有统计学意义(P<0.05)。结论:采用MTX宫颈预处理+宫腔镜电切术治疗子宫瘢痕妊娠效果显著,能够减少出血量,提高治疗效果,加快患者术后康复速度,且降低手术并发症发生率,值得在临床推广应用。
关键词: 子宫瘢痕妊娠;氨甲蝶呤;宫颈预处理;宫腔镜电切术;并发症

Clinicla effect of methotrexate cervical pretreatment + hysteroscopy in the treatment of uterine scar pregnancy

Authors: 1GUO Xiaoqiong, 1ZHOU Rongsheng, 1LU Yunlong
1 epartment of Obstetrics and Gynecology, Hefei Third People’s Hospital (Third Clinical Teaching Hospital of Anhui Medical University), Hefei 230022, China

CorrespondingAuthor: GUO Xiaoqiong Email: 88969964@qq.com

DOI: 10.3978/j.issn.2095-6959.2020.08.015

Abstract

Objective: To study the application and clinical effect of methotrexate (MTX) cervical pretreatment + hysteroscopy in the treatment of uterine scar pregnancy. Methods: A total of 80 patients with type I uterine scar pregnancy in Hefei Third People’s Hospital from January 2017 to December 2019 were included and divided into two groups according to the random number table method. The control group (n=50) were treated with intervention + hysterectomy, and the study group (n=30) were treated with MTX cervical pretreatment + hysteroscopy. The operation time, intraoperative blood loss, serum β-HCG recovery time and menstrual recovery time of the two groups were recorded and compared, and the clinical treatment effect and the incidence of complications were compared between the two groups. Results: After statistical analysis, the amount of intraoperative bleeding in the study group was significantly reduced after treatment, and the operation time, serum β-HCG recovery time and menstrual recovery time were significantly shortened. Compared with the control group, they had obvious advantages (P<0.05). After statistical analysis, the total effective rate of the research group after treatment was significantly superior to that of the control group (P<0.05). After statistical analysis, the incidence of complications after treatment in the study group was significantly superior to that in the control group (P<0.05). Conclusion: The use of MTX cervical pretreatment + hysteroscopic resection for uterine scar pregnancy has a significant effect, which can reduce the amount of bleeding, improve the treatment effect, speed up the postoperative recovery rate, and reduce the incidence of surgical complications, so the clinical has a positive promotion significance.
Keywords: uterine scar pregnancy; methotrexate; cervical pretreatment; hysteroscopic resection; complications