1 沧州市人民医院麻醉科，河北 沧州 061000
|| 沧州市科技支撑计划项目 (162302106)。
目的：研究并分析血液回收在大量异体红细胞悬液输注中的临床价值及对相关临床症状的改善效果。方法：选取100例本院于2016年8月至2019年8月三年间收治的急症大出血患者。通过将患者一般资料导入计算机，应用数字随机排列法分为对照组(50例，不应用血液回收直接输注异体红细胞悬液)和研究组(50例，悬液应用血液回收机洗涤后再进行输注)。对比两组患者输注后24 h临床症状存在率，生化检测中血气、凝血功能及体温变化及输注后并发症发生率。结果：经治疗后可知，研究组患者临床症状改善程度明显优于对照组；输注后24 h，研究组患者血气中pH，K+，LA均呈现出明显下降趋势，同时患者凝血情况中APTT、FIP及体温也得到明显改善，以上数据较对照组患者差异明显，有统计学意义(P<0.05)；同时在输注后研究组患者并发症发生率明显低于对照组，有统计学意义(P<0.05)。结论：通过在对急性大出血患者输注异体红细胞悬液前采用血液回收进行洗涤，输注后能在保证患者安全的同时进一步改善血气指标与凝血功能，并有助于患者体温尽快恢复至正常水平，具有较高的临床应用价值。
Clinical value of blood recovery in the transfusion of a large number of allogeneic red blood cell suspension and the effect of improving the clinical symptoms of patients
CorrespondingAuthor: GAO Xuelian
This work was supported by the Cangzhou Science and Technology Support Plan Project, China (162302106).
Objective: To study and analyze the clinical value of blood recovery in the transfusion of a large number of allogeneic red blood cell suspensions and the improvement effect on related clinical symptoms. Methods: 100 patients with acute massive hemorrhage admitted in our hospital from August 2016 to August 2019 were selected. By introducing the general data of patients into the computer, the patients were divided into 2 groups: the control group (50 cases, no use of blood recovery for direct transfusion of allogeneic red blood cell suspension) and the study group (50 cases, the suspension was washed by the blood recovery machine before transfusion). The clinical symptoms, blood gas, blood clotting function, body temperature and complications were compared between the 2 groups. Results: after treatment, the improvement of clinical symptoms in the study group was significantly better than that in the control group; 24 hours after infusion, the pH, K+, La in blood gas in the study group showed a significant downward trend, while APTT, FIP and body temperature in patients with coagulation were also significantly improved. The above data were significantly different from those in the control group (P<0.05); at the same time, the study was conducted after infusion. The incidence of complications in the study group was significantly lower than that in the control group (P<0.05). Conclusion: by washing the blood before transfusion of allogeneic red blood cell suspension in the patients with acute massive hemorrhage, the blood gas index and coagulation function can be further improved while ensuring the safety of the patients after transfusion, and the temperature of the patients can be restored to the normal level as soon as possible, which has higher clinical application value.
blood recovery; allogeneic red blood cell suspension; blood gas; coagulation function