文章摘要

良性阵发性位置性眩晕与炎症及氧化应激的研究进展

作者: 1蒋正会, 1任惠
1 昆明医科大学第一附属医院老年神经内科,昆明 650032
通讯: 任惠 Email: rh-3338@163.com
DOI: 10.3978/j.issn.2095-6959.2021.06.032
基金: 国家自然科学基金 (81860274)。

摘要

良性阵发性位置性眩晕(benign paroxysmal positional vertigo,BPPV)是最常见的前庭周围性眩晕之一。目前的研究认为炎症和氧化应激可能与BPPV的发病及复发相关,炎症及氧化应激标志物可作为BPPV诊断和复发的标志物。本综述旨在简要阐述炎症反应及氧化应激与BPPV的发病和复发的关系,分析炎症反应与氧化应激在钙代谢、维生素D缺乏、骨质疏松症、雌激素缺乏、高尿酸血症等代谢性疾病/紊乱与BPPV关系中的作用。
关键词: 良性阵发性位置性眩晕;炎症;氧化应激;代谢性疾病

Research progress of benign paroxysmal positional vertigo, inflammation, and oxidative stress

Authors: 1JIANG Zhenghui, 1REN Hui
1 Department of Geriatric Neurology, First Affiliated Hospital of Kunming Medical University, Kunming 650032, China

CorrespondingAuthor: REN Hui Email: rh-3338@163.com

DOI: 10.3978/j.issn.2095-6959.2021.06.032

Foundation: This work was supported by National Natural Science Foundation of China (81860247).

Abstract

Benign paroxysmal positional vertigo (BPPV) is one of the most common peripheral vestibular vertigo. Current researches show that inflammation and oxidative stress may be related to the pathogenesis and recurrence of BPPV, and inflammatory factors and oxidative stress markers can be used as markers for the diagnosis of BPPV and the predictors of its recurrence. This review is intended to briefly describes the relationship between inflammation and oxidative stress and the onset and recurrence of BPPV, and analyze its role in the relationship between BPPV and metabolic diseases/disorders such as calcium metabolism, vitamin D deficiency, osteoporosis, hyperuricemia, estrogen deficiency.
Keywords: benign paroxysmal positional vertigo; inflammation; oxidative stress; metabolic diseases