文章摘要

甘孜州高原地区3~7岁儿童维生素D营养状况与龋齿发病率的相关性

作者: 1罗晶, 1黄萍, 2林新梅, 3王全生, 4魏正蓉, 4巴学国, 4袁永潇, 5丁红燕, 5何茂云, 1李红梅, 1徐义兰, 1宋芳, 6董清科
1 泸州市人民医院儿童保健科,四川 泸州 646000
2 泸州市人民医院输血科,四川 泸州 646000
3 泸县中医医院康复科,四川 泸州 646100
4 甘孜州稻城县人民医院儿科,四川 甘孜 627750
5 甘孜州乡城县人民医院内科,四川 甘孜 627185
6 泸州市人民医院肿瘤科,四川 泸州 646000
通讯: 黄萍 Email: 1935855776@qq.com
DOI: 10.3978/j.issn.2095-6959.2021.07.026
基金: 四川省卫生与计划生育科研课题(17PJ277)。

摘要

目的:探讨四川省甘孜藏族自治州(以下简称甘孜州)高原地区3~7岁儿童维生素D[25-(OH)D]营养状况与龋齿发病率的关系。方法:2017年11月至2018年4月,选取四川省甘孜藏族自治州乡城县、稻城县3~7岁藏区儿童810名,检测血清25-(OH)D水平,调查儿童龋齿发生情况。结果:>6~7岁组龋齿发病率为57.44%,明显高于3~4岁组、>4~5岁组(P<0.05);>5~6岁组、>4~5岁组龋齿发病率为52.03%和43.68%,明显高于3~4岁组(P<0.05);>6~7岁组儿童血清25-(OH)D为(22.92±5.15) ng/mL,明显低于3~4岁组、>4~5岁组(P<0.05);>6~7岁组25-(OH)D缺乏或不足儿童龋齿发病率为62.34%,明显高于3~4岁组(P<0.05);>5~6岁组25-(OH)D缺乏或不足龋齿发病率为58.93%,明显高于3~4岁组(P<0.05)。结论:甘孜州高原地区3~7岁儿童龋齿、25-(OH)D缺乏或不足的比例较高,其中龋齿发生与25-(OH)D缺乏或不足有一定关系。
关键词: 高原地区;3~7岁儿童;维生素D;龋齿

Correlation between vitamin D status and dental caries incidence rate in children aged 3–7 years in Ganzi Prefecture

Authors: 1LUO Jing, 1HUANG Ping, 2LIN Xinmei, 3WANG Quansheng, 4WEI Zhengrong, 4BA Xueguo, 4YUAN Yongxiao, 5DING Hongyan, 5HE Maoyun, 1LI Hongmei, 1XU Yilan, 1SONG Fang, 6DONG Qingke
1 Department of Child Health Care, Luzhou People’s Hospital, Luzhou Sichuan 646000, China
2 Department of Blood Transfusion, Luzhou People’s Hospital, Luzhou Sichuan 646000, China
3 Department of Rehabilitation, Luxian Hospital of Traditional Chinese Medicine, Luzhou Sichuan 646100, China
4 Department of Pediatrics, People’s Hospital of Daocheng County, Ganzi Sichuan 627750, China
5 Department of Internal Medicine, People’s Hospital of Xiangcheng Ganzi Prefecture, Ganzi Sichuan 627185, China
6 Department of Oncology, Luzhou People’s Hospital, Luzhou Sichuan 646000, China

CorrespondingAuthor: HUANG Ping Email: 1935855776@qq.com

DOI: 10.3978/j.issn.2095-6959.2021.07.026

Foundation: This work was supported by the Health and Family Planning Research Project ofSichuan Province, China (17PJ277).

Abstract

Objective: To explore the relationship between vitamin D[25-(OH)D] nutrition status and dental caries incidence rate in 3–7 years old children in plateau area in Garzi Tibetan Autonomous Prefecture. Methods: From November 2017 to April 2018, 810 children aged 3–7 in Xiangcheng County and Daocheng County of Ganzi Tibetan Autonomous Prefecture in Sichuan Province were selected to test the serum 25-(OH) D level and investigate the occurrence of dental caries in children. Results: The incidence rate of dental caries in the group aged from >6–7 years was 57.44%, which was significantly higher than that in the 3–4 years old group and >4–5 years old group (P<0.05). The incidence rates of dental caries in >5–6 years old group and >4–5 years old group were 52.03% and 43.68%, which were significantly higher than that in 3–4 years old group (P<0.05). The serum 25-(OH)D was (22.92±5.15) ng/mL in the >6–7 years old group, which was significantly lower than that in the 3–4 years old group and >4–5 years old group (P<0.05). The incidence rate of dental caries in >6–7 years old group was 62.34%, which was significantly higher than that in 3–4 years old group (P<0.05). The incidence rate of dental caries in 25-(OH)D deficiency or insufficiency in >5–6 years old group was 58.93%, which was significantly higher than that in 3–4 years old group (P<0.05). Conclusion: The prevalence of dental caries and 25-(OH)D deficiency or insufficiency are higher in 3–7 years old children in the plateau area of Ganzi Prefecture. There is a certain relationship between dental caries and 25-(OH)D deficiency or insufficiency.
Keywords: plateau area; 3–7 years old children; vitamin D; dental caries