文章摘要

红黄煎剂联合八段锦对老年乳腺肿瘤化疗患者负性情绪、疲乏程度及生活质量的影响

作者: 1倪婷, 1孙莉, 1高玲, 1王娜, 1李梦婕, 1傳嘉欣, 1薛静娴
1 江苏省中医院乳腺外科,南京 210029
通讯: 孙莉 Email: llyyzz080105@yeah.net
DOI: 10.3978/j.issn.2095-6959.2021.09.007
基金: 江苏省自然科学基金(BK20191085)。

摘要

目的:探讨红黄煎剂联合八段锦应用于老年乳腺肿瘤化疗患者中的效果。方法:采用前瞻性双盲对照研究,选择2018年10月至2019年12月江苏省中医院收治的老年乳腺肿瘤化疗患者108例,按随机数字表法均分为对照组与观察组,对照组给予自制红黄煎剂干预,观察组在此基础上联合八段锦干预。另外选取单纯化疗患者54例,作为化疗组,对比3组干预前后血清一氧化碳(nitric oxide,NO)、超氧化物歧化酶(superoxide dismutase,SOD)含量、负性情绪、疲乏程度、生活质量变化情况。结果:3组化疗第7、14天的NO含量、SOD含量的差异均无统计学意义(均P>0.05)。观察组干预4个月后焦虑自评表(Self-Rating Anxiety Scale,SAS)、抑郁自评量表(Self-Rating Depression Scale,SDS)评分均低于对照组及化疗组(P<0.05)。观察组干预4个月后一般疲乏、现在疲乏、最疲乏及总分均低于对照组及化疗组(P<0.05)。观察组干预4个月后生理、情感、社会/家庭、附加关注、功能及总分均高于对照组及化疗组(P<0.05)。结论:自制红黄煎剂联合八段锦应用于老年乳腺肿瘤化疗患者效果显著,可缓解其负性情绪及疲乏程度,提升生活质量,值得在临床上推广应用。
关键词: 红黄煎剂;八段锦;老年;乳腺肿瘤;化疗

Effect of Honghuang decoction combined with Baduanjin on negative emotion, fatigue, and quality of life in elderly patients with breast cancer undergoing chemotherapy

Authors: 1NI Ting, 1SUN Li, 1GAO Ling, 1WANG Na, 1LI Mengjie, 1CHUAN Jiaxin, 1XUE Jingxian
1 Department of Breast Surgery, Jiangsu Provincial Hospital of Traditional Chinese Medicine, Nanjing 210029, China

CorrespondingAuthor: SUN Li Email: llyyzz080105@yeah.net

DOI: 10.3978/j.issn.2095-6959.2021.09.007

Foundation: This work was supported by the Natural Science Foundation of Jiangsu Province, China (BK20191085).

Abstract

Objective: To explore the effect of self-made Honghuang decoction combined with Baduanjin in the chemotherapy of elderly patients with breast tumors. Methods: A prospective, double-blind, controlled study was conducted, and 108 elderly patients with breast cancer treated with chemotherapy in our hospital from October 2018 to December 2019 were selected and randomly divided into two groups, 54 cases in each group. The control group was given self-made Honghuang decoction for intervention while the observation group was combined with Baduanjin intervention on this basis. In addition, 54 patients with chemotherapy alone were selected as the chemotherapy group, and the changes of serum NO, SOD content, negative emotion, fatigue degree and quality of life were compared among the 3 groups before and after intervention. Results: The NO content and SOD content of the 3 groups were compared on the 7th and 14th day of chemotherapy, and the difference was not statistically significant (P>0.05). The SAS and SDS scores of the observation group were lower than those of the control group and the chemotherapy group 4 months after the intervention (P<0.05). The observation group’s general fatigue, current fatigue, most fatigue, and total scores were lower than those of the control group and chemotherapy group 4 months after the intervention (P<0.05). The physical, emotional, social/family, additional attention, function, and total scores of the observation group were higher than those of the control group and the chemotherapy group 4 months after the intervention (P<0.05). Conclusion: The self-made Honghuang decoction combined with Baduanjin has a significant effect on the chemotherapy of elderly patients with breast tumors. It can relieve patients’ negative emotions and fatigue, and improve the quality of life. It is worth promoting.
Keywords: Honghuang decoction; Baduanjin; elderly patients; breast tumor; chemotherapy