1 中南大学湘雅三医院内分泌科，长沙 410000
A case of diabetic ketoacidosis caused by β-thalassemia secondary hematochromatosis
CorrespondingAuthor: MO Zhaohui Email: firstname.lastname@example.org
Foundation: This work was supported by the Natural Science Foundation of Hunan Province, China (2018JJ3804).
Hematochromatosis is caused by the excessive iron load in various organs and systems, which leads to dysfunction and a series of complications. According to the etiology, hematochromatosis can be grouped into primary and secondary forms. In this paper, we reported a case of beta thalassemia secondary hematochromatosis which was first diagnosed as diabetic ketoacidosis. The patient, male, 31-year-old, showed polyuria and polydipsia for 2 years, aggravation for more than 10 days, fatigue and poor appetite with nausea and vomiting for 2 days. Physical examination indicated skin pigmentation and liver enlargement. Laboratory tests suggested diabetic ketoacidosis, anemia and increased serum ferritin (SF). Finally, thalassemia gene test confirmed intermediate β-thalassemia. Therefore, when screening for associated causes in newly diagnosed diabetes, patients with high levels of ferritin, should be particularly alert for the occurrence of hematochromatosis.